Sodium pentobarbitone enhances responses of thalamic relay neurones to GABA in rat brain slices

Thalamic relay of afferent responses to 1- to 12-Hz whisker stimulation in the rat.

Somatosensory cortical neurons in the rat can be entrained to frequencies of pulsatile whisker stimulation up to at least 12 Hz. A recent study proposed that such entrainment depends on oscillatory corticothalamic feedback. According to this model, thalamic relay neurons function as comparators of ascending and descending signals and should vary their response magnitudes and latencies as a func...

Sodium di-n-propylacetate (valproate) potentiates responses to GABA and muscimol on single central neurones.

Clonazepam suppresses oscillations in rat thalamic slices

Hypersynchrony of spindle-like thalamic oscillations may contribute to thalamic dysrhythmias including generalized absence epilepsy. Here we show that, as predicted by previous modeling studies, enhancement of inhibition between thalamic reticular (RE) cells by clonazepam suppresses evoked oscillations in rat thalamic slices. We also observed spontaneous oscillations, which have a variable and ...

Evaluation of GABA Receptors of Ventral Tegmental Area in Cardiovascular Responses in Rat

Background: The ventral tegmental area (VTA) is well known for its role in cardiovascular control. It is demonstrated that about 20-30% of the VTA neurons are GABAergic though their role in cardiovascular control is not yet understood. This study is carried out to find the effects of GABA A and GABA B receptors on cardiovascular response of the VTA. Methods: Experiments were performed on uretha...

RAPID COMMUNICATION Thalamic Relay of Afferent Responses to 1- to 12-Hz Whisker Stimulation in the Rat

Hartings, Jed A. and Daniel J. Simons. Thalamic relay of afferent As a consequence, thalamic responses phase-lag the cortical responses to 1to 12-Hz whisker stimulation in the rat. J. Neurooscillations. physiol. 80: 1016–1019, 1998. Somatosensory cortical neurons in According to the PLL model, the phase difference sigthe rat can be entrained to frequencies of pulsatile whisker stimulanaled by t...